AirHint found the following cheapest return flights from Prague (PRG) to Luxemburg (LUX) in September 2025 (see full year).

Return flights

04 Sep - 11 Sep	Ryanair
29 Sep - 05 Oct	Luxair	direct
06 Sep - 08 Sep	Lufthansa
05 Sep - 08 Sep	Lufthansa
17 Sep - 19 Sep	Wizz Air UK
05 Sep - 12 Sep	Lufthansa
05 Sep - 07 Sep	Lufthansa
18 Sep - 21 Sep	Lufthansa
08 Sep - 12 Sep	Ryanair
08 Sep - 15 Sep	Lufthansa
05 Sep - 07 Sep	Luxair	direct

Also check the deals for one-way flights from Prague to Luxemburg in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Luxemburg in September from 138€

Return flights