AirHint found the following cheapest return flights from Prague (PRG) to Skiathos (JSI) in September 2025 (see full year).

Return flights

08 Sep - 11 Sep	Ryanair	direct
08 Sep - 18 Sep	Ryanair	direct
25 Sep - 23 Oct	Ryanair
29 Sep - 23 Oct	Ryanair
01 Sep - 08 Sep	Ryanair	direct
22 Sep - 25 Sep	Ryanair	direct
11 Sep - 18 Sep	Ryanair	direct
08 Sep - 25 Sep	Ryanair	direct
01 Sep - 11 Sep	Ryanair	direct
08 Sep - 22 Sep	Ryanair	direct
08 Sep - 15 Sep	Ryanair	direct
25 Sep - 01 Oct	Ryanair
04 Sep - 08 Sep	Ryanair
29 Sep - 02 Oct	Ryanair
25 Sep - 02 Oct	Ryanair
29 Sep - 10 Oct	Ryanair
26 Sep - 23 Oct	Ryanair
25 Sep - 27 Oct	Ryanair
29 Sep - 31 Oct	Ryanair
29 Sep - 04 Oct	Ryanair

Also check the deals for one-way flights from Prague to Skiathos in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Skiathos in September from 123€

Return flights