AirHint found the following cheapest return flights from Prague (PRG) to Skiathos (JSI) in September 2025 (see full year).

Return flights

15 Sep - 18 Sep	Ryanair	direct
11 Sep - 18 Sep	Ryanair	direct
25 Sep - 02 Oct	Ryanair
22 Sep - 02 Oct	Ryanair
18 Sep - 24 Sep	Ryanair
15 Sep - 24 Sep	Ryanair
22 Sep - 25 Sep	Ryanair	direct
11 Sep - 17 Sep	Ryanair
15 Sep - 25 Sep	Ryanair
22 Sep - 01 Oct	Ryanair
15 Sep - 25 Sep	Ryanair	direct
15 Sep - 20 Sep	Ryanair
22 Sep - 29 Sep	Ryanair
25 Sep - 03 Oct	Ryanair
16 Sep - 07 Oct	Ryanair
30 Sep - 05 Oct	Lufthansa
29 Sep - 01 Oct	SKY express
15 Sep - 01 Oct	SKY express
27 Sep - 01 Oct	SKY express
19 Sep - 01 Oct	SKY express

Also check the deals for one-way flights from Prague to Skiathos in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Skiathos in September from 130€

Return flights