AirHint found the following cheapest return flights from Prague (PRG) to Istanbul (IST) in November 2025 (see full year).

Return flights

05 Nov - 26 Nov	Wizz Air UK
21 Nov - 23 Nov	Wizz Air UK
11 Nov - 16 Nov	Ryanair
17 Nov - 22 Nov	Ryanair
06 Nov - 08 Nov	Pegasus Airlines
08 Nov - 13 Nov	Pegasus Airlines	direct
28 Nov - 30 Nov	easyJet
20 Nov - 23 Nov	LOT
17 Nov - 24 Nov	Wizz Air Malta
01 Nov - 08 Nov	LOT
30 Nov - 16 Dec	SKY express
20 Nov - 05 Dec	Fly One
18 Nov - 05 Dec	Fly One
30 Nov - 12 Dec	SKY express
30 Nov - 05 Dec	SKY express
23 Nov - 12 Dec	SKY express
23 Nov - 05 Dec	SKY express
30 Nov - 20 Dec	SKY express
16 Nov - 05 Dec	SKY express
30 Nov - 11 Dec	SKY express

Also check the deals for one-way flights from Prague to Istanbul in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Istanbul in November from 129€

Return flights