AirHint found the following cheapest return flights from Prague (PRG) to Duesseldorf (DUS) in October 2025 (see full year).

Return flights

02 Oct - 05 Oct	Eurowings	direct
30 Oct - 03 Nov	Eurowings	direct
14 Oct - 31 Oct	Eurowings	direct
21 Oct - 23 Oct	Eurowings	direct
10 Oct - 25 Oct	easyJet
20 Oct - 27 Oct	easyJet
01 Oct - 02 Oct	easyJet
30 Oct - 02 Nov	Eurowings	direct
29 Oct - 01 Nov	easyJet
17 Oct - 19 Oct	easyJet
10 Oct - 13 Oct	Ryanair
03 Oct - 05 Oct	Ryanair
20 Oct - 27 Oct	Eurowings	direct

Also check the deals for one-way flights from Prague to Duesseldorf in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Duesseldorf in October from 102€

Return flights