AirHint found the following cheapest return flights from Prague (PRG) to Cancun (CUN) in September 2025 (see full year).

Return flights

10 Sep - 24 Sep	Ryanair
11 Sep - 27 Sep	Ryanair
20 Sep - 11 Oct	Ryanair
24 Sep - 21 Oct	Wizz Air UK
25 Sep - 21 Oct	Condor
09 Sep - 21 Sep	Condor
03 Sep - 11 Sep	Ryanair
14 Sep - 27 Sep	Condor
29 Sep - 02 Oct	Transavia France
11 Sep - 18 Sep	Ryanair
09 Sep - 16 Sep	Transavia France
01 Sep - 15 Sep	easyJet
30 Sep - 22 Oct	Condor
24 Sep - 20 Oct	Air Canada

Also check the deals for one-way flights from Prague to Cancun in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Prague to Cancun in September from 592€

Return flights