AirHint found the following cheapest return flights from Prague (PRG) to Rome (CIA) in April 2026 (see full year).

Return flights

14 Apr - 30 Apr	Ryanair	direct
14 Apr - 05 May	Ryanair	direct
03 Apr - 14 Apr	Ryanair	direct
14 Apr - 14 Apr	Ryanair	direct
01 Apr - 14 Apr	Ryanair	direct
03 Apr - 11 Apr	Ryanair	direct
11 Apr - 30 Apr	Ryanair	direct
11 Apr - 14 Apr	Ryanair	direct
01 Apr - 11 Apr	Ryanair	direct
06 Apr - 14 Apr	Ryanair	direct
03 Apr - 09 Apr	Ryanair	direct
30 Apr - 05 May	Ryanair	direct
30 Apr - 11 May	Ryanair	direct
30 Apr - 17 May	Ryanair	direct

Also check the deals for one-way flights from Prague to Rome in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome

Cheapest return flights from Prague to Rome in April from 139€

Return flights