AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (SAW) in October 2025 (see full year).

Return flights

08 Oct - 15 Oct	Ryanair
01 Oct - 07 Oct	Volotea
15 Oct - 18 Oct	Ryanair
17 Oct - 20 Oct	Ryanair
11 Oct - 14 Oct	ITA Airways
20 Oct - 24 Oct	easyJet
09 Oct - 12 Oct	Ryanair
24 Oct - 27 Oct	ITA Airways
10 Oct - 12 Oct	Volotea
09 Oct - 13 Oct	Ryanair
27 Oct - 03 Nov	Ryanair
27 Oct - 04 Nov	Ryanair
12 Oct - 12 Nov	Ryanair
11 Oct - 07 Nov	Ryanair
11 Oct - 06 Nov	Ryanair

Also check the deals for one-way flights from Palermo to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul

Cheapest return flights from Palermo to Istanbul in October from 161€

Return flights