AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (SAW) in October 2025 (see full year).

Return flights

22 Oct - 29 Oct	Ryanair
22 Oct - 28 Oct	Ryanair
20 Oct - 24 Oct	Aeroitalia
15 Oct - 17 Oct	Ryanair
15 Oct - 20 Oct	Ryanair
13 Oct - 17 Oct	Aeroitalia
16 Oct - 22 Oct	Ryanair
16 Oct - 19 Oct	Ryanair
24 Oct - 28 Oct	Ryanair
15 Oct - 18 Oct	Ryanair
30 Oct - 03 Nov	Ryanair
27 Oct - 02 Nov	Ryanair
31 Oct - 03 Nov	Ryanair
31 Oct - 05 Nov	Ryanair
25 Oct - 02 Nov	Ryanair
29 Oct - 02 Nov	Ryanair
31 Oct - 07 Nov	Ryanair
30 Oct - 02 Nov	Ryanair
31 Oct - 02 Nov	Ryanair
31 Oct - 04 Nov	Aeroitalia

Also check the deals for one-way flights from Palermo to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Palermo to Istanbul in October from 162€

Return flights