AirHint found the following cheapest return flights from Palermo (PMO) to Prague (PRG) in April 2026 (see full year).

Return flights

15 Apr - 18 Apr	easyJet
14 Apr - 18 Apr	easyJet
16 Apr - 19 Apr	Ryanair
17 Apr - 21 Apr	easyJet
29 Apr - 02 May	easyJet
24 Apr - 27 Apr	SWISS
29 Apr - 04 May	SWISS
10 Apr - 12 Apr	SWISS
17 Apr - 20 Apr	SWISS
23 Apr - 26 Apr	SWISS
05 Apr - 08 Apr	easyJet
24 Apr - 26 Apr	SWISS
30 Apr - 05 May	SWISS
30 Apr - 04 May	SWISS
30 Apr - 02 May	SWISS
23 Apr - 11 May	Vueling Airlines
23 Apr - 06 May	Vueling Airlines
30 Apr - 11 May	Vueling Airlines
29 Apr - 11 May	Vueling Airlines
30 Apr - 06 May	Vueling Airlines

Also check the deals for one-way flights from Palermo to Prague in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Palermo to Prague in April from 97€

Return flights