AirHint found the following cheapest return flights from Palermo (PMO) to Istanbul (IST) in May 2026 (see full year).

Return flights

07 May - 14 May	Turkish Airlines	direct
02 May - 06 May	Turkish Airlines	direct
04 May - 11 May	Turkish Airlines	direct
01 May - 04 May	Turkish Airlines	direct
04 May - 08 May	Turkish Airlines	direct
14 May - 21 May	Turkish Airlines	direct
01 May - 05 May	Turkish Airlines
19 May - 21 May	Volotea
29 May - 02 Jun	Ryanair

Also check the deals for one-way flights from Palermo to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Palermo to Istanbul in May from 240€

Return flights