AirHint found the following cheapest return flights from Pittsburgh (PIT) to Rome (FCO) in September 2025 (see full year).

Return flights

09 Sep - 17 Sep	Spirit Airlines
29 Sep - 08 Oct	Spirit Airlines
18 Sep - 25 Sep	Spirit Airlines
15 Sep - 22 Sep	Spirit Airlines
18 Sep - 22 Sep	jetBlue
17 Sep - 25 Sep	Spirit Airlines
09 Sep - 21 Sep	Spirit Airlines
05 Sep - 21 Sep	Spirit Airlines
09 Sep - 16 Sep	United
03 Sep - 10 Sep	United
30 Sep - 07 Oct	United
24 Sep - 01 Oct	United
01 Sep - 08 Sep	United
27 Sep - 04 Oct	United

Also check the deals for one-way flights from Pittsburgh to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Pittsburgh to Rome in September from 394€

Return flights