AirHint found the following cheapest return flights from Portland (PDX) to San Francisco (SFO) in October 2025 (see full year).

Return flights

01 Oct - 08 Oct	United	direct
01 Oct - 06 Oct	United	direct
08 Oct - 11 Oct	United	direct
11 Oct - 14 Oct	United	direct
14 Oct - 16 Oct	United	direct
02 Oct - 06 Oct	United	direct
09 Oct - 13 Oct	United	direct
10 Oct - 13 Oct	United	direct
24 Oct - 26 Oct	Frontier Airlines
05 Oct - 30 Oct	Frontier Airlines

Also check the deals for one-way flights from Portland to San Francisco in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Portland to San Francisco in October from 83€

Return flights