AirHint found the following cheapest return flights from Bucharest (OTP) to Prague (PRG) in September 2025 (see full year).

Return flights

17 Sep - 22 Sep	Aeroitalia
19 Sep - 22 Sep	Aeroitalia
08 Sep - 11 Sep	Wizz Air Malta
15 Sep - 17 Sep	Ryanair
27 Sep - 29 Sep	TAROM
03 Sep - 07 Sep	Ryanair
01 Sep - 03 Sep	Air Serbia
08 Sep - 10 Sep	Ryanair
01 Sep - 07 Sep	Air Serbia
17 Sep - 23 Sep	Ryanair

Also check the deals for one-way flights from Bucharest to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Bucharest to Prague in September from 116€

Return flights