Cheapest return flights from Chicago to Panama City in October from 245€

AirHint found the following cheapest return flights from Chicago (ORD) to Panama City (PTY) in October 2025 (see full year).

Return flights

23 Oct - 27 Oct Avianca
28 Oct - 04 Nov Avianca
25 Oct - 02 Nov Avianca
17 Oct - 21 Oct Avianca
02 Oct - 05 Oct Copa direct
23 Oct - 27 Oct Copa direct
17 Oct - 21 Oct Copa direct
06 Oct - 09 Oct Copa direct
15 Oct - 22 Oct Copa direct
18 Oct - 24 Oct Copa direct
17 Oct - 19 Oct Copa direct
10 Oct - 18 Oct Copa direct
10 Oct - 10 Nov Copa direct
25 Oct - 02 Nov Copa direct
28 Oct - 04 Nov Copa direct

Also check the deals for one-way flights from Chicago to Panama City in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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