Cheapest return flights from Chicago to Panama City in October from 454€

AirHint found the following cheapest return flights from Chicago (ORD) to Panama City (PTY) in October 2025 (see full year).

Return flights

08 Oct - 11 Nov Avianca
10 Oct - 18 Oct Avianca
10 Oct - 18 Oct Copa direct
08 Oct - 11 Nov Copa direct

Also check the deals for one-way flights from Chicago to Panama City in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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