AirHint found the following cheapest return flights from Chicago (ORD) to Prague (PRG) in May 2026 (see full year).

Return flights

01 May - 04 May	LOT
11 May - 22 May	Turkish Airlines
13 May - 03 Jun	Finnair
19 May - 02 Jun	Finnair
16 May - 30 May	LOT
10 May - 16 May	Icelandair
13 May - 18 Jun	Finnair
01 May - 08 May	Icelandair
11 May - 16 May	Turkish Airlines
18 May - 25 May	Finnair
21 May - 28 May	Finnair
26 May - 02 Jun	Aer Lingus
25 May - 09 Jun	Austrian Airlines
13 May - 07 Jun	Delta

Also check the deals for one-way flights from Chicago to Prague in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Prague in May from 448€

Return flights