AirHint found the following cheapest return flights from Chicago (ORD) to Istanbul (IST) in May 2026 (see full year).

Return flights

15 May - 22 May	Icelandair
04 May - 14 May	SWISS
05 May - 19 May	KLM
01 May - 23 May	TAP
18 May - 08 Jun	Air France
08 May - 22 May	Air France
27 May - 20 Jun	Aer Lingus
04 May - 14 May	Turkish Airlines	direct
05 May - 19 May	Turkish Airlines	direct
08 May - 22 May	Turkish Airlines	direct
01 May - 23 May	Turkish Airlines	direct
15 May - 22 May	Turkish Airlines	direct
18 May - 08 Jun	Turkish Airlines	direct
27 May - 20 Jun	Turkish Airlines	direct

Also check the deals for one-way flights from Chicago to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Istanbul in May from 674€

Return flights