AirHint found the following cheapest return flights from Chicago (ORD) to Istanbul (IST) in May 2026 (see full year).

Return flights

04 May - 12 May	ITA Airways
11 May - 30 Jun	KLM
01 May - 26 May	Icelandair
19 May - 26 May	Icelandair
01 May - 28 May	KLM
20 May - 31 May	KLM
25 May - 08 Jun	KLM
22 May - 05 Jun	KLM
01 May - 28 May	Turkish Airlines	direct
15 May - 17 May	KLM
04 May - 12 May	Turkish Airlines	direct
15 May - 17 May	Turkish Airlines	direct
22 May - 05 Jun	Turkish Airlines	direct
20 May - 31 May	Turkish Airlines	direct
25 May - 08 Jun	Turkish Airlines	direct

Also check the deals for one-way flights from Chicago to Istanbul in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Istanbul in May from 604€

Return flights