AirHint found the following cheapest return flights from Chicago (ORD) to Istanbul (IST) in December 2025 (see full year).

Return flights

31 Dec - 14 Jan	Air France
28 Dec - 11 Jan	Air France
24 Dec - 31 Dec	Air France
01 Dec - 15 Dec	Air France
14 Dec - 28 Dec	Air France
01 Dec - 15 Dec	Turkish Airlines	direct
21 Dec - 31 Dec	Air France
31 Dec - 14 Jan	Turkish Airlines	direct
23 Dec - 31 Dec	Air France
23 Dec - 30 Dec	KLM
28 Dec - 11 Jan	Turkish Airlines	direct
26 Dec - 03 Jan	Air France
22 Dec - 04 Jan	Air France
24 Dec - 31 Dec	Turkish Airlines	direct
26 Dec - 03 Jan	Turkish Airlines	direct
23 Dec - 30 Dec	Turkish Airlines	direct
14 Dec - 28 Dec	Turkish Airlines	direct
22 Dec - 04 Jan	Turkish Airlines	direct

Also check the deals for one-way flights from Chicago to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Istanbul in December from 635€

Return flights