AirHint found the following cheapest return flights from Chicago (ORD) to Istanbul (IST) in December 2025 (see full year).

Return flights

02 Dec - 08 Dec	Icelandair
02 Dec - 09 Dec	Icelandair
01 Dec - 08 Dec	Icelandair
02 Dec - 10 Dec	Icelandair
10 Dec - 19 Jan	Icelandair
10 Dec - 19 Dec	Icelandair
30 Dec - 24 Jan	Icelandair
08 Dec - 12 Dec	KLM
01 Dec - 27 Dec	KLM
05 Dec - 12 Dec	KLM
30 Dec - 13 Jan	KLM
02 Dec - 07 Dec	KLM
11 Dec - 11 Jan	KLM
11 Dec - 19 Jan	Air France
06 Dec - 27 Dec	Air France
13 Dec - 10 Jan	Frontier Airlines
28 Dec - 17 Jan	KLM
29 Dec - 25 Jan	KLM
27 Dec - 16 Jan	Spirit Airlines
13 Dec - 08 Jan	Frontier Airlines

Also check the deals for one-way flights from Chicago to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Istanbul in December from 468€

Return flights