AirHint found the following cheapest return flights from Porto (OPO) to Prague (PRG) in September 2025 (see full year).

Return flights

30 Sep - 04 Oct	easyJet
24 Sep - 27 Sep	easyJet
24 Sep - 01 Oct	easyJet
25 Sep - 29 Sep	easyJet
22 Sep - 29 Sep	Wizz Air Malta
25 Sep - 27 Sep	easyJet
27 Sep - 29 Sep	easyJet
30 Sep - 03 Oct	easyJet
27 Sep - 01 Oct	easyJet
10 Sep - 17 Sep	easyJet
14 Sep - 17 Sep	easyJet
10 Sep - 15 Sep	easyJet
17 Sep - 20 Sep	easyJet
20 Sep - 22 Sep	easyJet
30 Sep - 11 Oct	Vueling Airlines
30 Sep - 07 Oct	Vueling Airlines
23 Sep - 11 Oct	Vueling Airlines
29 Sep - 11 Oct	Vueling Airlines
30 Sep - 18 Oct	Vueling Airlines
24 Sep - 11 Oct	Vueling Airlines

Also check the deals for one-way flights from Porto to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Porto to Prague in September from 122€

Return flights