AirHint found the following cheapest return flights from Porto (OPO) to Prague (PRG) in September 2025 (see full year).

Return flights

24 Sep - 30 Sep	easyJet
24 Sep - 01 Oct	easyJet
24 Sep - 27 Sep	easyJet
17 Sep - 23 Sep	easyJet
18 Sep - 22 Sep	easyJet
17 Sep - 17 Sep	easyJet
25 Sep - 29 Sep	easyJet
27 Sep - 30 Sep	easyJet
27 Sep - 01 Oct	easyJet
25 Sep - 27 Sep	easyJet
03 Sep - 09 Sep	easyJet
17 Sep - 20 Sep	easyJet
25 Sep - 02 Oct	easyJet
24 Sep - 14 Oct	Vueling Airlines
23 Sep - 14 Oct	Vueling Airlines
24 Sep - 06 Oct	Vueling Airlines
23 Sep - 06 Oct	Vueling Airlines
30 Sep - 14 Oct	Vueling Airlines
29 Sep - 14 Oct	Vueling Airlines
24 Sep - 15 Oct	Vueling Airlines

Also check the deals for one-way flights from Porto to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague

Cheapest return flights from Porto to Prague in September from 130€

Return flights