AirHint found the following cheapest return flights from Porto (OPO) to Prague (PRG) in September 2025 (see full year).

Return flights

19 Sep - 22 Sep	Wizz Air Malta
17 Sep - 24 Sep	Wizz Air Malta
08 Sep - 10 Sep	Wizz Air Malta
19 Sep - 23 Sep	Wizz Air Malta
24 Sep - 24 Sep	Ryanair
24 Sep - 29 Sep	Ryanair
24 Sep - 27 Sep	easyJet
22 Sep - 22 Sep	Volotea
29 Sep - 06 Oct	Wizz Air Malta
17 Sep - 19 Sep	easyJet
12 Sep - 15 Sep	Wizz Air Malta
27 Sep - 01 Oct	easyJet
25 Sep - 04 Oct	easyJet
29 Sep - 02 Oct	easyJet
24 Sep - 06 Oct	Vueling Airlines
15 Sep - 06 Oct	Vueling Airlines
27 Sep - 06 Oct	Vueling Airlines
24 Sep - 11 Oct	Vueling Airlines
30 Sep - 06 Oct	Vueling Airlines
23 Sep - 06 Oct	Vueling Airlines

Also check the deals for one-way flights from Porto to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Porto to Prague in September from 117€

Return flights