AirHint found the following cheapest return flights from New York (NYC) to Santiago (SCL) in September 2025 (see full year).

Return flights

10 Sep - 18 Sep	Frontier Airlines
18 Sep - 02 Oct	Avianca
01 Sep - 08 Sep	Frontier Airlines
12 Sep - 19 Sep	Frontier Airlines
05 Sep - 12 Sep	Frontier Airlines
12 Sep - 20 Sep	Frontier Airlines
04 Sep - 04 Oct	LATAM Airlines Group
14 Sep - 25 Sep	Spirit Airlines
01 Sep - 08 Sep	Delta	direct
04 Sep - 27 Sep	LATAM Airlines Group
21 Sep - 30 Sep	Frontier Airlines
04 Sep - 27 Sep	Delta	direct

Also check the deals for one-way flights from New York to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago

Cheapest return flights from New York to Santiago in September from 497€

Return flights