AirHint found the following cheapest return flights from New York (NYC) to Panama City (PTY) in September 2025 (see full year).

Return flights

04 Sep - 08 Sep	Spirit Airlines
11 Sep - 16 Sep	Spirit Airlines
11 Sep - 13 Sep	Spirit Airlines
11 Sep - 12 Sep	Spirit Airlines
02 Sep - 09 Sep	Spirit Airlines
18 Sep - 21 Sep	Spirit Airlines
12 Sep - 19 Sep	Spirit Airlines
06 Sep - 13 Sep	Spirit Airlines
06 Sep - 08 Sep	Frontier Airlines
18 Sep - 22 Sep	Frontier Airlines
26 Sep - 10 Oct	Spirit Airlines
29 Sep - 06 Oct	Frontier Airlines
29 Sep - 06 Oct	Copa	direct
10 Sep - 17 Oct	United	direct
26 Sep - 10 Oct	United	direct

Also check the deals for one-way flights from New York to Panama City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from New York to Panama City in September from 321€

Return flights