AirHint found the following cheapest return flights from Naples (NAP) to Istanbul (IST) in September 2025 (see full year).

Return flights

29 Sep - 01 Oct	Wizz Air Malta
03 Sep - 08 Sep	Volotea
17 Sep - 24 Sep	Wizz Air Malta
03 Sep - 10 Sep	Volotea
09 Sep - 13 Sep	Wizz Air
24 Sep - 01 Oct	Wizz Air Malta
29 Sep - 04 Oct	Ryanair
09 Sep - 12 Sep	Wizz Air
08 Sep - 12 Sep	Wizz Air Malta
16 Sep - 22 Sep	Wizz Air
08 Sep - 10 Sep	Wizz Air Malta
24 Sep - 25 Sep	Wizz Air Malta
24 Sep - 26 Sep	Wizz Air Malta
29 Sep - 03 Oct	Wizz Air Malta
29 Sep - 02 Oct	Ryanair
28 Sep - 03 Oct	easyJet
28 Sep - 05 Oct	easyJet
29 Sep - 01 Oct	Turkish Airlines	direct
29 Sep - 02 Oct	Turkish Airlines	direct
29 Sep - 03 Oct	Turkish Airlines	direct

Also check the deals for one-way flights from Naples to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Naples to Istanbul in September from 140€

Return flights