AirHint found the following cheapest return flights from Naples (NAP) to Istanbul (IST) in April 2026 (see full year).

Return flights

05 Apr - 08 Apr	easyJet
04 Apr - 08 Apr	easyJet
27 Apr - 04 May	easyJet
29 Apr - 04 May	easyJet
05 Apr - 11 Apr	easyJet
19 Apr - 22 Apr	easyJet
20 Apr - 24 Apr	Air Serbia
24 Apr - 27 Apr	Air Serbia
29 Apr - 05 May	easyJet
05 Apr - 06 Apr	easyJet
17 Apr - 22 Apr	easyJet
26 Apr - 02 May	easyJet
20 Apr - 25 Apr	easyJet
11 Apr - 14 Apr	Lufthansa
30 Apr - 04 May	easyJet
30 Apr - 04 May	Turkish Airlines	direct
29 Apr - 04 May	Turkish Airlines	direct
29 Apr - 05 May	Turkish Airlines	direct
30 Apr - 05 May	easyJet
26 Apr - 02 May	Turkish Airlines	direct

Also check the deals for one-way flights from Naples to Istanbul in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Naples to Istanbul in April from 166€

Return flights