AirHint found the following cheapest return flights from Milano (MXP) to Santiago (SCL) in September 2025 (see full year).

Return flights

18 Sep - 25 Sep	Delta
16 Sep - 24 Sep	Delta
25 Sep - 16 Oct	Delta
18 Sep - 23 Sep	Delta
17 Sep - 21 Sep	Delta
30 Sep - 06 Oct	Delta
24 Sep - 30 Sep	Delta
27 Sep - 11 Oct	Wizz Air Malta
19 Sep - 28 Sep	Delta
19 Sep - 26 Sep	Delta
30 Sep - 04 Oct	Ryanair
27 Sep - 13 Oct	Wizz Air Malta
26 Sep - 16 Oct	easyJet
26 Sep - 03 Oct	Condor
30 Sep - 05 Oct	Air France

Also check the deals for one-way flights from Milano to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Milano to Santiago in September from 702€

Return flights