AirHint found the following cheapest return flights from Milano (MXP) to Santiago (SCL) in December 2025 (see full year).

Return flights

05 Dec - 17 Dec	Air Canada
04 Dec - 29 Jan	Delta
05 Dec - 16 Dec	Air Canada
09 Dec - 30 Dec	Delta
01 Dec - 14 Dec	Turkish Airlines
05 Dec - 08 Dec	LATAM Airlines Group
02 Dec - 28 Jan	LATAM Airlines Group
09 Dec - 13 Jan	Delta
25 Dec - 20 Jan	Delta
31 Dec - 31 Jan	LATAM Airlines Group
01 Dec - 15 Dec	LATAM Airlines Group
10 Dec - 27 Jan	LATAM Airlines Group
06 Dec - 08 Dec	Delta
06 Dec - 16 Dec	LATAM Airlines Group
05 Dec - 23 Jan	Royal Air Maroc
12 Dec - 16 Jan	Royal Air Maroc
13 Dec - 29 Dec	Transavia France
13 Dec - 11 Jan	Ryanair
04 Dec - 24 Dec	Air France
29 Dec - 16 Jan	Wizz Air Malta

Also check the deals for one-way flights from Milano to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Milano to Santiago in December from 716€

Return flights