AirHint found the following cheapest return flights from Milano (MXP) to Panama City (PTY) in December 2025 (see full year).

Return flights

01 Dec - 14 Dec	Air Europa
06 Dec - 08 Dec	Air Europa
05 Dec - 13 Dec	Air Europa
31 Dec - 21 Jan	Turkish Airlines
14 Dec - 20 Dec	Turkish Airlines
31 Dec - 22 Jan	Condor
31 Dec - 19 Jan	Condor
31 Dec - 20 Jan	Air Europa
08 Dec - 15 Jan	Condor
30 Dec - 19 Jan	Turkish Airlines
11 Dec - 13 Jan	United
30 Dec - 20 Jan	Turkish Airlines
30 Dec - 22 Jan	Turkish Airlines
29 Dec - 22 Jan	Condor
13 Dec - 27 Dec	Turkish Airlines
12 Dec - 27 Dec	Turkish Airlines
24 Dec - 31 Dec	Vueling Airlines
17 Dec - 31 Dec	Turkish Airlines
22 Dec - 31 Dec	Turkish Airlines
21 Dec - 31 Dec	Turkish Airlines

Also check the deals for one-way flights from Milano to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Milano to Panama City in December from 586€

Return flights