AirHint found the following cheapest return flights from Milano (MXP) to Panama City (PTY) in December 2025 (see full year).

Return flights

03 Dec - 10 Dec	Air France
23 Dec - 10 Jan	Turkish Airlines
23 Dec - 07 Jan	Turkish Airlines
30 Dec - 10 Jan	Turkish Airlines
24 Dec - 10 Jan	Turkish Airlines
29 Dec - 10 Jan	Turkish Airlines
15 Dec - 05 Jan	Turkish Airlines
23 Dec - 05 Jan	Turkish Airlines
24 Dec - 05 Jan	Turkish Airlines
31 Dec - 10 Jan	Air France
22 Dec - 10 Jan	Turkish Airlines
21 Dec - 28 Dec	Air France

Also check the deals for one-way flights from Milano to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Milano to Panama City in December from 647€

Return flights