AirHint found the following cheapest return flights from Miami (MIA) to Santiago (SCL) in September 2025 (see full year).

Return flights

16 Sep - 21 Sep	Arajet
11 Sep - 25 Sep	Arajet
17 Sep - 28 Sep	Avianca
12 Sep - 25 Sep	Avianca
13 Sep - 27 Sep	Avianca
15 Sep - 16 Sep	Avianca
15 Sep - 21 Sep	Avianca
15 Sep - 15 Oct	Avianca
17 Sep - 22 Sep	Avianca
29 Sep - 06 Oct	Avianca
15 Sep - 06 Oct	Avianca
10 Sep - 17 Sep	Sky Airline
10 Sep - 28 Sep	Sky Airline
23 Sep - 02 Oct	Sky Airline
23 Sep - 01 Oct	Sky Airline
22 Sep - 01 Oct	Avianca
21 Sep - 01 Oct	Frontier Airlines
15 Sep - 06 Oct	Delta	direct
15 Sep - 15 Oct	Delta	direct

Also check the deals for one-way flights from Miami to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Miami to Santiago in September from 396€

Return flights