AirHint found the following cheapest return flights from Mexico City (MEX) to Santo Domingo (SDQ) in December 2025 (see full year).

Return flights

03 Dec - 10 Dec	Arajet	direct
15 Dec - 24 Dec	Aeromexico	direct
10 Dec - 18 Dec	Aeromexico	direct
23 Dec - 01 Jan	Avianca
17 Dec - 24 Dec	Aeromexico	direct
19 Dec - 02 Jan	Arajet	direct
09 Dec - 17 Dec	Copa
30 Dec - 13 Jan	Copa
08 Dec - 13 Dec	Avianca
06 Dec - 11 Dec	Avianca
30 Dec - 13 Jan	Aeromexico	direct
23 Dec - 01 Jan	Aeromexico	direct
07 Dec - 13 Dec	Avianca
15 Dec - 15 Dec	Avianca
31 Dec - 04 Jan	Copa
29 Dec - 03 Jan	Copa
13 Dec - 20 Dec	Avianca
27 Dec - 02 Jan	Copa
19 Dec - 03 Jan	Arajet
19 Dec - 04 Jan	Arajet

Also check the deals for one-way flights from Mexico City to Santo Domingo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Santo Domingo in December from 239€

Return flights