AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in November 2025 (see full year).

Return flights

20 Nov - 24 Nov	Avianca
11 Nov - 15 Nov	Avianca
18 Nov - 28 Nov	Avianca
08 Nov - 15 Nov	Avianca
26 Nov - 02 Dec	Avianca
12 Nov - 19 Nov	Avianca
14 Nov - 21 Nov	Avianca
10 Nov - 17 Nov	Avianca
11 Nov - 25 Nov	Avianca
22 Nov - 02 Dec	Avianca
15 Nov - 22 Nov	Avianca
10 Nov - 20 Nov	Avianca
20 Nov - 04 Dec	Avianca
01 Nov - 23 Dec	LATAM Airlines Group
23 Nov - 03 Dec	Avianca
06 Nov - 05 Dec	Avianca
28 Nov - 12 Dec	LATAM Airlines Group
22 Nov - 02 Dec	Aeromexico	direct
23 Nov - 03 Dec	Aeromexico	direct
01 Nov - 23 Dec	Aeromexico	direct

Also check the deals for one-way flights from Mexico City to Santiago in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Santiago in November from 471€

Return flights