AirHint found the following cheapest return flights from Mexico City (MEX) to Santiago (SCL) in November 2025 (see full year).

Return flights

12 Nov - 17 Nov	Avianca
23 Nov - 13 Dec	Avianca
23 Nov - 02 Dec	Avianca
18 Nov - 25 Nov	Avianca
22 Nov - 29 Nov	Avianca
17 Nov - 25 Nov	Avianca
15 Nov - 22 Nov	Avianca
14 Nov - 17 Nov	Avianca
15 Nov - 29 Nov	Avianca
30 Nov - 05 Dec	Avianca
18 Nov - 02 Dec	Avianca
30 Nov - 06 Dec	Avianca
12 Nov - 16 Nov	Avianca
06 Nov - 10 Nov	Avianca
24 Nov - 30 Nov	Avianca
07 Nov - 07 Dec	Avianca
07 Nov - 07 Dec	Aeromexico	direct
30 Nov - 27 Dec	Arajet
23 Nov - 02 Dec	Aeromexico	direct
23 Nov - 13 Dec	Aeromexico	direct

Also check the deals for one-way flights from Mexico City to Santiago in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Santiago in November from 450€

Return flights