AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in May 2026 (see full year).

Return flights

11 May - 16 May	Avianca
12 May - 20 May	Avianca
13 May - 19 May	Avianca
18 May - 26 May	Avianca
19 May - 26 May	Avianca
25 May - 28 May	Avianca
13 May - 20 May	Avianca
15 May - 18 May	Avianca
21 May - 28 May	Avianca
03 May - 08 May	Avianca
27 May - 04 Jun	Avianca
28 May - 04 Jun	Avianca
27 May - 06 Jun	Avianca
27 May - 04 Jun	Copa	direct
27 May - 15 Jun	Copa	direct
28 May - 04 Jun	Copa	direct
22 May - 08 Jun	Viva
25 May - 08 Jun	Viva
22 May - 06 Jun	Viva
17 May - 06 Jun	Viva

Also check the deals for one-way flights from Mexico City to Panama City in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Panama City in May from 221€

Return flights