AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in May 2026 (see full year).

Return flights

12 May - 24 May	Aeromexico	direct
01 May - 05 May	Avianca
21 May - 25 May	Avianca
13 May - 26 May	Avianca
07 May - 18 May	Avianca
13 May - 26 May	Copa	direct
07 May - 18 May	Copa	direct
01 May - 08 May	Avianca
01 May - 08 May	Copa	direct
21 May - 31 May	Avianca
29 May - 08 Jun	Aeromexico	direct
27 May - 15 Jun	Copa	direct

Also check the deals for one-way flights from Mexico City to Panama City in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Panama City in May from 260€

Return flights