AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in May 2026 (see full year).

Return flights

01 May - 04 May	Avianca
12 May - 16 May	Avianca
26 May - 26 May	Avianca
19 May - 23 May	Avianca
03 May - 08 May	Avianca
13 May - 27 May	Avianca
22 May - 30 May	Avianca
19 May - 19 May	Avianca
30 May - 01 Jun	Avianca
31 May - 01 Jun	Avianca
01 May - 04 May	Copa	direct
03 May - 08 May	Copa	direct
28 May - 02 Jun	Copa	direct
27 May - 02 Jun	Copa	direct
30 May - 01 Jun	Copa	direct
31 May - 01 Jun	Aeromexico	direct

Also check the deals for one-way flights from Mexico City to Panama City in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Panama City in May from 214€

Return flights