AirHint found the following cheapest return flights from Mexico City (MEX) to Panama City (PTY) in October 2026 (see full year).

Return flights

01 Oct - 08 Oct	Avianca
09 Oct - 23 Oct	Avianca
08 Oct - 23 Oct	Avianca
28 Oct - 02 Nov	Avianca
01 Oct - 08 Oct	Copa	direct
09 Oct - 23 Oct	Copa	direct
08 Oct - 23 Oct	Copa	direct
28 Oct - 02 Nov	Copa	direct
02 Oct - 08 Oct	Viva
01 Oct - 02 Oct	Viva
28 Oct - 29 Oct	Viva
09 Oct - 29 Oct	Viva

Also check the deals for one-way flights from Mexico City to Panama City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Cheapest return flights from Mexico City to Panama City in October from 369€

Return flights