AirHint found the following cheapest return flights from Mexico City (MEX) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

30 Dec - 26 Jan	Copa
24 Dec - 29 Jan	Avianca
30 Dec - 27 Jan	Copa
31 Dec - 21 Jan	Aeromexico
24 Dec - 25 Jan	Copa
30 Dec - 01 Jan	Aeromexico
23 Dec - 30 Dec	LATAM Airlines Group
23 Dec - 01 Jan	LATAM Airlines Group
24 Dec - 01 Jan	LATAM Airlines Group
25 Dec - 01 Jan	Avianca
25 Dec - 31 Dec	Avianca
30 Dec - 14 Jan	Aeromexico
25 Dec - 30 Dec	LATAM Airlines Group
24 Dec - 31 Dec	Arajet
22 Dec - 30 Dec	LATAM Airlines Group
24 Dec - 31 Dec	Aeromexico	direct
23 Dec - 30 Dec	LATAM Airlines Group	direct
24 Dec - 29 Dec	Copa
21 Dec - 26 Dec	LATAM Airlines Group
25 Dec - 29 Dec	LATAM Airlines Group

Also check the deals for one-way flights from Mexico City to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Sao Paulo in December from 434€

Return flights