AirHint found the following cheapest return flights from Mexico City (MEX) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

02 Dec - 10 Dec	Arajet
01 Dec - 09 Dec	LATAM Airlines Group
06 Dec - 08 Dec	Copa
05 Dec - 11 Dec	Copa
04 Dec - 09 Dec	Copa
14 Dec - 19 Dec	LATAM Airlines Group	direct
03 Dec - 09 Dec	Copa
03 Dec - 11 Dec	Copa
05 Dec - 10 Dec	Copa
04 Dec - 07 Dec	Copa
24 Dec - 25 Jan	LATAM Airlines Group	direct
26 Dec - 26 Jan	LATAM Airlines Group	direct
21 Dec - 02 Jan	LATAM Airlines Group	direct
29 Dec - 21 Jan	LATAM Airlines Group	direct
25 Dec - 25 Jan	LATAM Airlines Group	direct
30 Dec - 14 Jan	Aeromexico
24 Dec - 14 Jan	Arajet
29 Dec - 14 Jan	Copa
28 Dec - 14 Jan	Copa
24 Dec - 15 Jan	Arajet

Also check the deals for one-way flights from Mexico City to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Sao Paulo in December from 381€

Return flights