AirHint found the following cheapest return flights from Mexico City (MEX) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

02 Dec - 10 Dec	Arajet
22 Dec - 27 Jan	Avianca
01 Dec - 08 Dec	Avianca
04 Dec - 11 Dec	Avianca
03 Dec - 09 Dec	Avianca
02 Dec - 09 Dec	Avianca
02 Dec - 08 Dec	Avianca
16 Dec - 24 Dec	Arajet
02 Dec - 08 Dec	LATAM Airlines Group	direct
03 Dec - 09 Dec	LATAM Airlines Group	direct
02 Dec - 09 Dec	LATAM Airlines Group	direct
22 Dec - 27 Jan	LATAM Airlines Group	direct
25 Dec - 07 Jan	Arajet
22 Dec - 01 Jan	Avianca
22 Dec - 12 Jan	LATAM Airlines Group
27 Dec - 02 Jan	Avianca
13 Dec - 06 Jan	Avianca
29 Dec - 06 Jan	Avianca
16 Dec - 06 Jan	Avianca
25 Dec - 08 Jan	Avianca

Also check the deals for one-way flights from Mexico City to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Sao Paulo in December from 379€

Return flights