AirHint found the following cheapest return flights from Mexico City (MEX) to Sao Paulo (GRU) in December 2025 (see full year).

Return flights

03 Dec - 05 Dec	Copa
24 Dec - 23 Jan	Copa
25 Dec - 23 Jan	Copa
04 Dec - 10 Dec	Arajet
03 Dec - 11 Dec	Copa
05 Dec - 12 Dec	Copa
24 Dec - 23 Jan	LATAM Airlines Group	direct
07 Dec - 14 Dec	Copa
04 Dec - 13 Dec	Copa
07 Dec - 11 Dec	Copa
03 Dec - 10 Dec	Copa
02 Dec - 10 Dec	Copa
29 Dec - 13 Jan	LATAM Airlines Group
31 Dec - 16 Jan	LATAM Airlines Group
24 Dec - 31 Dec	LATAM Airlines Group
26 Dec - 23 Jan	Aeromexico	direct
29 Dec - 14 Jan	LATAM Airlines Group
25 Dec - 14 Jan	LATAM Airlines Group
30 Dec - 14 Jan	LATAM Airlines Group
25 Dec - 01 Jan	Copa

Also check the deals for one-way flights from Mexico City to Sao Paulo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Sao Paulo in December from 404€

Return flights