AirHint found the following cheapest return flights from Mexico City (MEX) to Rome (FCO) in September 2025 (see full year).

Return flights

10 Sep - 24 Sep	Aeromexico
08 Sep - 19 Sep	Aeromexico
13 Sep - 19 Sep	Aeromexico
10 Sep - 22 Sep	Aeromexico
13 Sep - 24 Sep	Aeromexico
10 Sep - 17 Sep	Aeromexico
12 Sep - 19 Sep	Aeromexico
22 Sep - 01 Oct	Aeromexico
05 Sep - 31 Oct	Aeromexico
05 Sep - 26 Sep	Aeromexico
10 Sep - 16 Sep	Aeromexico
10 Sep - 20 Sep	Aeromexico
30 Sep - 14 Oct	Air Canada
24 Sep - 07 Oct	Air Canada
24 Sep - 28 Oct	Aeromexico
25 Sep - 08 Oct	Arajet
21 Sep - 02 Oct	Aeromexico
27 Sep - 02 Oct	Aeromexico
29 Sep - 06 Oct	Aeromexico
29 Sep - 16 Oct	Aeromexico

Also check the deals for one-way flights from Mexico City to Rome in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Mexico City to Rome in September from 608€

Return flights