AirHint found the following cheapest return flights from Melbourne (MEL) to Santiago (SCL) in October 2025 (see full year).

Return flights

20 Oct - 11 Nov	LATAM Airlines Group
29 Oct - 09 Nov	Qantas
30 Oct - 10 Nov	LATAM Airlines Group
29 Oct - 09 Nov	LATAM Airlines Group	direct
30 Oct - 06 Nov	Qantas
22 Oct - 12 Nov	LATAM Airlines Group	direct
22 Oct - 13 Nov	Qantas
11 Oct - 15 Nov	LATAM Airlines Group	direct
12 Oct - 16 Nov	LATAM Airlines Group
22 Oct - 13 Nov	LATAM Airlines Group	direct
12 Oct - 19 Oct	LATAM Airlines Group
12 Oct - 22 Oct	LATAM Airlines Group
22 Oct - 29 Oct	LATAM Airlines Group
11 Oct - 21 Oct	Qantas
11 Oct - 21 Oct	LATAM Airlines Group	direct
08 Oct - 17 Oct	Qantas
14 Oct - 21 Oct	Qantas
06 Oct - 15 Oct	LATAM Airlines Group
08 Oct - 30 Oct	LATAM Airlines Group

Also check the deals for one-way flights from Melbourne to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Melbourne to Santiago in October from 1042€

Return flights