Cheapest return flights from Chicago to Panama City in December from 473€

AirHint found the following cheapest return flights from Chicago (MDW) to Panama City (PTY) in December 2025 (see full year).

Return flights

07 Dec - 11 Dec Frontier Airlines
04 Dec - 10 Dec Frontier Airlines
01 Dec - 10 Dec Delta
01 Dec - 14 Dec Delta
01 Dec - 04 Dec Delta
02 Dec - 06 Dec Delta
23 Dec - 31 Dec Frontier Airlines
11 Dec - 16 Dec Delta
11 Dec - 15 Dec Delta
22 Dec - 02 Jan Frontier Airlines
27 Dec - 04 Jan Frontier Airlines
27 Dec - 02 Jan Delta
27 Dec - 03 Jan Delta

Also check the deals for one-way flights from Chicago to Panama City in December.

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