AirHint found the following cheapest return flights from Chicago (MDW) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

04 Dec - 10 Dec	Frontier Airlines
01 Dec - 07 Dec	Frontier Airlines
11 Dec - 16 Dec	Frontier Airlines
19 Dec - 23 Dec	Frontier Airlines
20 Dec - 01 Jan	Frontier Airlines
26 Dec - 02 Jan	Frontier Airlines
24 Dec - 31 Dec	LATAM Airlines Group
10 Dec - 01 Jan	LATAM Airlines Group

Also check the deals for one-way flights from Chicago to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Rio Negro in December from 412€

Return flights