AirHint found the following cheapest return flights from Chicago (MDW) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

15 Dec - 24 Dec	Frontier Airlines
24 Dec - 30 Dec	Frontier Airlines
23 Dec - 30 Dec	Frontier Airlines
24 Dec - 06 Jan	Frontier Airlines
01 Dec - 04 Dec	Frontier Airlines
20 Dec - 01 Jan	Frontier Airlines
25 Dec - 06 Jan	Frontier Airlines
20 Dec - 06 Jan	Frontier Airlines
20 Dec - 07 Jan	Frontier Airlines
25 Dec - 31 Jan	LATAM Airlines Group

Also check the deals for one-way flights from Chicago to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rio Negro

Cheap car rent in Rio Negro

Cheapest return flights from Chicago to Rio Negro in December from 373€

Return flights