AirHint found the following cheapest return flights from Chicago (MDW) to Rome (FCO) in December 2025 (see full year).

Return flights

07 Dec - 18 Dec	Air France
03 Dec - 10 Dec	Delta
09 Dec - 16 Dec	Delta
03 Dec - 09 Dec	KLM
30 Dec - 14 Jan	Delta
31 Dec - 16 Jan	Air France
11 Dec - 18 Dec	Delta
05 Dec - 13 Dec	Frontier Airlines
11 Dec - 22 Dec	KLM
05 Dec - 14 Dec	Delta
11 Dec - 14 Dec	Delta
03 Dec - 27 Dec	Air France
30 Dec - 10 Jan	Delta
22 Dec - 17 Jan	Air France
30 Dec - 08 Jan	Frontier Airlines
18 Dec - 13 Jan	Delta
23 Dec - 17 Jan	Frontier Airlines
18 Dec - 10 Jan	Frontier Airlines
12 Dec - 11 Jan	Delta
30 Dec - 07 Jan	Delta

Also check the deals for one-way flights from Chicago to Rome in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Chicago to Rome in December from 413€

Return flights