AirHint found the following cheapest return flights from Rio Negro (MDE) to Madrid (MAD) in December 2025 (see full year).

Return flights

07 Dec - 21 Jan	Air Europa	direct
31 Dec - 29 Jan	Avianca
24 Dec - 07 Jan	LATAM Airlines Group
01 Dec - 30 Jan	Avianca
26 Dec - 16 Jan	JetSmart
31 Dec - 18 Jan	Avianca
01 Dec - 30 Jan	Air Europa	direct
05 Dec - 16 Jan	Avianca
23 Dec - 18 Jan	Avianca
16 Dec - 20 Jan	Avianca
08 Dec - 30 Dec	Air Europa	direct
04 Dec - 31 Dec	Avianca
02 Dec - 29 Dec	Avianca
02 Dec - 12 Dec	Avianca
02 Dec - 29 Dec	Air Europa	direct
24 Dec - 31 Dec	Avianca
03 Dec - 18 Dec	Turkish Airlines
21 Dec - 28 Dec	Avianca
09 Dec - 23 Dec	Air Europa	direct
03 Dec - 10 Dec	Avianca

Also check the deals for one-way flights from Rio Negro to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Madrid in December from 736€

Return flights