AirHint found the following cheapest return flights from Rio Negro (MDE) to Madrid (MAD) in December 2025 (see full year).

Return flights

07 Dec - 21 Jan	Avianca	direct
31 Dec - 29 Jan	Avianca
31 Dec - 20 Jan	Avianca
31 Dec - 19 Jan	Avianca	direct
31 Dec - 14 Jan	Avianca
15 Dec - 30 Jan	Avianca
23 Dec - 22 Jan	Air Europa	direct
16 Dec - 28 Jan	Air Europa	direct
24 Dec - 07 Jan	Avianca
12 Dec - 10 Jan	Avianca
25 Dec - 31 Dec	Air Europa	direct
07 Dec - 26 Dec	Avianca	direct
17 Dec - 30 Dec	Avianca
11 Dec - 30 Dec	Avianca
01 Dec - 15 Dec	Avianca	direct
20 Dec - 26 Dec	Avianca
11 Dec - 27 Dec	Iberia
11 Dec - 27 Dec	Air Europa	direct
08 Dec - 23 Dec	Avianca
16 Dec - 27 Dec	Air Europa	direct

Also check the deals for one-way flights from Rio Negro to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Madrid in December from 710€

Return flights