AirHint found the following cheapest return flights from Rio Negro (MDE) to Madrid (MAD) in November 2025 (see full year).

Return flights

03 Nov - 12 Nov	JetSmart
06 Nov - 17 Nov	Copa
13 Nov - 20 Nov	JetSmart
07 Nov - 21 Nov	JetSmart
13 Nov - 21 Nov	JetSmart
10 Nov - 21 Nov	JetSmart
04 Nov - 18 Nov	JetSmart
04 Nov - 19 Nov	JetSmart
04 Nov - 20 Nov	JetSmart
08 Nov - 25 Nov	JetSmart
27 Nov - 31 Dec	Avianca
26 Nov - 03 Dec	Avianca	direct
24 Nov - 08 Dec	Avianca	direct
18 Nov - 03 Dec	Avianca
28 Nov - 12 Dec	Avianca
19 Nov - 05 Dec	Avianca	direct
17 Nov - 14 Dec	Spirit Airlines
29 Nov - 11 Dec	Avianca
23 Nov - 03 Dec	Avianca	direct
21 Nov - 05 Dec	Avianca	direct

Also check the deals for one-way flights from Rio Negro to Madrid in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Madrid in November from 602€

Return flights