AirHint found the following cheapest return flights from Rio Negro (MDE) to Madrid (MAD) in November 2025 (see full year).

Return flights

12 Nov - 02 Dec	Avianca
03 Nov - 17 Nov	Avianca	direct
14 Nov - 18 Nov	Avianca
03 Nov - 18 Nov	Avianca
02 Nov - 17 Nov	Avianca	direct
12 Nov - 26 Nov	JetSmart
17 Nov - 24 Nov	Wingo
03 Nov - 12 Nov	Avianca
04 Nov - 12 Nov	Avianca
03 Nov - 10 Nov	Avianca	direct
14 Nov - 18 Nov	Air Europa	direct
27 Nov - 31 Dec	Avianca
18 Nov - 04 Dec	JetSmart
19 Nov - 04 Dec	JetSmart
09 Nov - 09 Dec	Avianca
17 Nov - 10 Dec	Avianca
10 Nov - 10 Dec	Avianca
16 Nov - 10 Dec	Avianca
21 Nov - 27 Dec	Avianca
09 Nov - 09 Dec	Air Europa	direct

Also check the deals for one-way flights from Rio Negro to Madrid in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Madrid in November from 702€

Return flights