AirHint found the following cheapest return flights from Rio Negro (MDE) to Sao Paulo (GRU) in December 2025 (see full year).
Return flights
| 30 Dec - 23 Jan | Copa | ||
| 30 Dec - 06 Jan | Copa | ||
| 30 Dec - 03 Jan | Copa |
Also check the deals for one-way flights from Rio Negro to Sao Paulo in December.
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