AirHint found the following cheapest return flights from Manchester (MAN) to Karachi (KHI) in September 2025 (see full year).

Return flights

04 Sep - 10 Oct	Eurowings
04 Sep - 17 Sep	Ryanair
11 Sep - 25 Sep	Ryanair
01 Sep - 17 Sep	Ryanair
10 Sep - 24 Sep	Eurowings
16 Sep - 04 Oct	Ryanair
05 Sep - 19 Sep	Vueling Airlines
04 Sep - 18 Sep	Ryanair
26 Sep - 14 Oct	Ryanair
06 Sep - 01 Oct	Ryanair
03 Sep - 17 Sep	Eurowings
26 Sep - 24 Oct	Pegasus Airlines
20 Sep - 17 Oct	Pegasus Airlines
12 Sep - 25 Sep	Ryanair
12 Sep - 19 Sep	Ryanair
12 Sep - 27 Sep	Ryanair
22 Sep - 09 Oct	Ryanair
30 Sep - 02 Oct	Ryanair
13 Sep - 02 Oct	Ryanair
18 Sep - 04 Oct	Ryanair

Also check the deals for one-way flights from Manchester to Karachi in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Manchester to Karachi in September from 366€

Return flights