AirHint found the following cheapest return flights from Manchester (MAN) to Istanbul (IST) in September 2025 (see full year).

Return flights

29 Sep - 15 Oct	easyJet	direct
22 Sep - 06 Oct	easyJet	direct
29 Sep - 06 Oct	easyJet	direct
12 Sep - 12 Oct	easyJet	direct
20 Sep - 27 Sep	Pegasus Airlines
22 Sep - 24 Sep	easyJet	direct
28 Sep - 01 Oct	easyJet	direct
03 Sep - 17 Sep	easyJet	direct
17 Sep - 23 Sep	Ryanair
22 Sep - 29 Sep	easyJet	direct
10 Sep - 17 Sep	easyJet	direct
18 Sep - 24 Sep	Pegasus Airlines
06 Sep - 17 Sep	Pegasus Airlines
12 Sep - 23 Sep	easyJet
20 Sep - 24 Sep	Pegasus Airlines
29 Sep - 05 Oct	easyJet	direct
28 Sep - 09 Oct	easyJet
28 Sep - 09 Oct	easyJet	direct
24 Sep - 01 Oct	easyJet	direct
26 Sep - 01 Oct	easyJet	direct

Also check the deals for one-way flights from Manchester to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Manchester to Istanbul in September from 127€

Return flights