AirHint found the following cheapest return flights from Manchester (MAN) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

15 Sep - 15 Oct	KLM
10 Sep - 15 Oct	KLM
30 Sep - 21 Oct	KLM
18 Sep - 13 Oct	Ryanair
18 Sep - 08 Oct	TAP
19 Sep - 11 Oct	KLM
01 Sep - 22 Sep	Air France
12 Sep - 05 Oct	Air France
19 Sep - 24 Sep	KLM
20 Sep - 12 Oct	Air France
12 Sep - 15 Sep	Vueling Airlines
05 Sep - 08 Sep	Ryanair
01 Sep - 01 Oct	Air France
11 Sep - 26 Sep	KLM
01 Sep - 10 Sep	Ryanair
01 Sep - 15 Sep	Ryanair
05 Sep - 26 Sep	Air France
12 Sep - 29 Sep	Delta
22 Sep - 29 Sep	Delta
28 Sep - 11 Oct	Air France

Also check the deals for one-way flights from Manchester to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Manchester to Sao Paulo in September from 672€

Return flights