AirHint found the following cheapest return flights from Manchester (MAN) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

11 Sep - 17 Oct	Air France
01 Sep - 08 Sep	TAP
07 Sep - 28 Sep	KLM
12 Sep - 29 Sep	TAP
21 Sep - 27 Sep	TAP
10 Sep - 20 Sep	TAP
09 Sep - 17 Oct	KLM
06 Sep - 17 Oct	Air France
10 Sep - 21 Sep	TAP
18 Sep - 21 Oct	Air France
10 Sep - 23 Sep	TAP
06 Sep - 18 Sep	TAP
12 Sep - 05 Oct	KLM
10 Sep - 17 Sep	TAP
08 Sep - 29 Sep	easyJet
07 Sep - 03 Oct	Vueling Airlines

Also check the deals for one-way flights from Manchester to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Manchester to Sao Paulo in September from 668€

Return flights