AirHint found the following cheapest return flights from Manchester (MAN) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

10 Sep - 15 Oct	KLM
19 Sep - 12 Oct	Air France
18 Sep - 12 Oct	Air France
18 Sep - 08 Oct	Air France
21 Sep - 12 Oct	Air France
11 Sep - 17 Oct	Air France
20 Sep - 12 Oct	Air France
22 Sep - 12 Oct	Ryanair
12 Sep - 05 Oct	KLM
04 Sep - 17 Sep	Vueling Airlines
18 Sep - 13 Oct	Air France
12 Sep - 19 Sep	Ryanair
12 Sep - 29 Sep	Air France
03 Sep - 19 Sep	Vueling Airlines
17 Sep - 26 Sep	Ryanair
10 Sep - 23 Sep	KLM
10 Sep - 13 Sep	easyJet
15 Sep - 25 Sep	Air France
13 Sep - 17 Sep	Ryanair
04 Sep - 12 Sep	Ryanair

Also check the deals for one-way flights from Manchester to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Manchester to Sao Paulo in September from 672€

Return flights