AirHint found the following cheapest return flights from Madrid (MAD) to Santa Cruz (VVI) in December 2025 (see full year).

Return flights

02 Dec - 09 Dec	Avianca
01 Dec - 31 Jan	Avianca
01 Dec - 08 Dec	Avianca
01 Dec - 15 Dec	Azul Airlines
10 Dec - 25 Dec	Wizz Air Malta
12 Dec - 20 Dec	Ryanair
08 Dec - 20 Dec	Iberia
07 Dec - 20 Jan	Avianca
05 Dec - 25 Dec	Ryanair
10 Dec - 16 Jan	Wizz Air Malta
14 Dec - 20 Jan	Wizz Air Malta
26 Dec - 28 Jan	Avianca
26 Dec - 27 Jan	Avianca
07 Dec - 12 Jan	Ryanair
10 Dec - 18 Jan	Wizz Air Malta
12 Dec - 23 Jan	Ryanair
13 Dec - 13 Jan	Wizz Air Malta
04 Dec - 31 Dec	Avianca
08 Dec - 20 Dec	Air Europa	direct
10 Dec - 31 Dec	Wizz Air Malta

Also check the deals for one-way flights from Madrid to Santa Cruz in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santa Cruz in December from 864€

Return flights