AirHint found the following cheapest one-way flights from Madrid (MAD) to Santa Cruz (VVI) in December 2025 (see full year).
One-Way flights
| 28 Dec | Air Europa | direct | |
| 30 Dec | Vueling Airlines | ||
| 27 Dec | LATAM Airlines Group | ||
| 26 Dec | KLM | ||
| 24 Dec | TAP | ||
| 26 Dec | Iberia | direct | |
| 24 Dec | Boliviana de Aviacion | direct | |
| 22 Dec | TAP |
Also check the deals for return flights from Madrid to Santa Cruz in December.
Powered by
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
Find us on social media