Cheapest one-way flights from Madrid to Santa Cruz in December from 399€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santa Cruz (VVI) in December 2026 (see full year).

One-Way flights

03 Dec LATAM Airlines Group
04 Dec LATAM Airlines Group
21 Dec LATAM Airlines Group
22 Dec LATAM Airlines Group
23 Dec LATAM Airlines Group
18 Dec LATAM Airlines Group
19 Dec LATAM Airlines Group
20 Dec LATAM Airlines Group
17 Dec Avianca
04 Dec Iberia direct

Also check the deals for return flights from Madrid to Santa Cruz in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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