AirHint found the following cheapest return flights from Madrid (MAD) to Quito (UIO) in September 2025 (see full year).

Return flights

03 Sep - 24 Sep	Delta
10 Sep - 05 Oct	Delta
18 Sep - 28 Sep	Avianca
22 Sep - 16 Oct	Avianca
11 Sep - 26 Sep	Avianca
02 Sep - 29 Sep	Avianca
05 Sep - 29 Sep	Avianca
01 Sep - 23 Sep	Avianca
07 Sep - 23 Sep	Avianca
24 Sep - 10 Oct	Avianca
08 Sep - 22 Sep	Avianca
09 Sep - 22 Sep	Avianca
05 Sep - 27 Sep	Avianca
08 Sep - 08 Oct	Avianca
21 Sep - 21 Oct	Avianca
21 Sep - 07 Oct	Avianca
23 Sep - 08 Oct	Avianca
15 Sep - 16 Oct	Avianca
22 Sep - 23 Oct	Avianca
29 Sep - 27 Oct	Delta

Also check the deals for one-way flights from Madrid to Quito in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Quito in September from 675€

Return flights