AirHint found the following cheapest return flights from Madrid (MAD) to Quito (UIO) in October 2025 (see full year).

Return flights

01 Oct - 30 Oct	Avianca
31 Oct - 09 Nov	Avianca
22 Oct - 29 Oct	Avianca
01 Oct - 31 Oct	Avianca
22 Oct - 04 Nov	Avianca
28 Oct - 18 Nov	Avianca
30 Oct - 06 Nov	Delta
21 Oct - 28 Oct	Iberia	direct
30 Oct - 06 Nov	Iberia	direct
25 Oct - 08 Nov	Iberia
25 Oct - 14 Nov	Iberia
23 Oct - 04 Nov	Iberia	direct
30 Oct - 08 Nov	Iberia	direct
30 Oct - 10 Nov	Iberia	direct
05 Oct - 18 Oct	Avianca
13 Oct - 26 Oct	Avianca
02 Oct - 16 Oct	Avianca
16 Oct - 30 Oct	Avianca
02 Oct - 06 Oct	Avianca
22 Oct - 29 Oct	Iberia	direct

Also check the deals for one-way flights from Madrid to Quito in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Quito

Cheap car rent in Quito

Cheapest return flights from Madrid to Quito in October from 729€

Return flights