AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in May 2026 (see full year).

Return flights

13 May - 27 May	Avianca
14 May - 26 May	Avianca
12 May - 26 May	Avianca
05 May - 27 May	Avianca
16 May - 27 May	Avianca
08 May - 27 May	Avianca
18 May - 24 May	Avianca
11 May - 20 May	Avianca
09 May - 22 May	Avianca
08 May - 24 May	Avianca
19 May - 03 Jun	Delta
26 May - 03 Jun	Delta
07 May - 04 Jun	LATAM Airlines Group	direct
25 May - 10 Jun	LATAM Airlines Group
26 May - 03 Jun	Iberia	direct
16 May - 04 Jun	Avianca
29 May - 20 Jun	Turkish Airlines

Also check the deals for one-way flights from Madrid to Santiago in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santiago in May from 591€

Return flights