AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in May 2026 (see full year).

Return flights

01 May - 22 May	Avianca
01 May - 15 May	Avianca
18 May - 25 May	Avianca
18 May - 24 May	Avianca
17 May - 24 May	Avianca
16 May - 24 May	Avianca
04 May - 29 May	Avianca
19 May - 29 May	Avianca
01 May - 12 May	Avianca
08 May - 10 May	Avianca
28 May - 10 Jun	LATAM Airlines Group
08 May - 06 Jun	Iberia	direct
28 May - 10 Jun	Iberia	direct
30 May - 10 Jun	LATAM Airlines Group
30 May - 10 Jun	Iberia	direct

Also check the deals for one-way flights from Madrid to Santiago in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santiago in May from 636€

Return flights