Cheapest one-way flights from Madrid to Santiago in May from 396€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCL) in May 2026 (see full year).

One-Way flights

25 May Azul Airlines
17 May LATAM Airlines Group
01 May LATAM Airlines Group
25 May LATAM Airlines Group direct
07 May LATAM Airlines Group direct
07 May Azul Airlines
16 May LATAM Airlines Group direct
05 May Azul Airlines
26 May Avianca
31 May Avianca

Also check the deals for return flights from Madrid to Santiago in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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