AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in November 2025 (see full year).

Return flights

10 Nov - 25 Nov	SWISS
10 Nov - 24 Nov	SWISS
10 Nov - 26 Nov	SWISS
10 Nov - 04 Dec	SWISS
15 Nov - 10 Dec	SWISS
19 Nov - 26 Nov	SWISS
22 Nov - 29 Nov	SWISS
19 Nov - 29 Nov	SWISS
19 Nov - 03 Dec	SWISS
14 Nov - 26 Nov	Delta
13 Nov - 26 Nov	Delta
06 Nov - 16 Nov	Delta
14 Nov - 27 Nov	Delta
23 Nov - 02 Dec	Delta
23 Nov - 03 Dec	Delta
24 Nov - 03 Dec	Delta
06 Nov - 03 Dec	Delta
26 Nov - 03 Dec	Delta
24 Nov - 07 Dec	Delta
23 Nov - 07 Dec	Delta

Also check the deals for one-way flights from Madrid to Santiago in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santiago in November from 697€

Return flights