AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in November 2025 (see full year).

Return flights

23 Nov - 31 Dec	Air Canada
25 Nov - 31 Dec	Air Canada
15 Nov - 09 Dec	Air Canada
16 Nov - 02 Dec	Air Canada
11 Nov - 18 Nov	Air Canada
10 Nov - 17 Nov	Delta
06 Nov - 16 Nov	Delta
06 Nov - 15 Nov	Delta
12 Nov - 22 Nov	Delta
07 Nov - 14 Nov	Delta
05 Nov - 21 Nov	Delta
07 Nov - 15 Nov	Delta
07 Nov - 23 Nov	Delta
10 Nov - 16 Nov	Delta
03 Nov - 02 Dec	Air Canada
24 Nov - 07 Dec	Delta
24 Nov - 06 Dec	Delta
20 Nov - 06 Dec	Delta
20 Nov - 07 Dec	Delta
14 Nov - 01 Dec	Delta

Also check the deals for one-way flights from Madrid to Santiago in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santiago in November from 623€

Return flights