Cheapest one-way flights from Madrid to Santiago in November from 450€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Santiago (SCL) in November 2025 (see full year).

One-Way flights

20 Nov LATAM Airlines Group
24 Nov WORLD2FLY
21 Nov LATAM Airlines Group
30 Nov Azul Airlines
23 Nov Air Canada
17 Nov WORLD2FLY
25 Nov Transavia France
19 Nov Air Canada
22 Nov SWISS
28 Nov LATAM Airlines Group

Also check the deals for return flights from Madrid to Santiago in November.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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