AirHint found the following cheapest return flights from Madrid (MAD) to Prague (PRG) in April 2026 (see full year).

Return flights

04 Apr - 11 Apr	Iberia	direct
11 Apr - 14 Apr	Iberia	direct
10 Apr - 13 Apr	Iberia	direct
24 Apr - 27 Apr	Iberia	direct
07 Apr - 08 Apr	Smart Wings	direct
29 Apr - 04 May	Iberia
01 Apr - 07 Apr	Iberia	direct
17 Apr - 20 Apr	Air Europa
06 Apr - 10 Apr	Smart Wings
15 Apr - 19 Apr	Iberia	direct
01 Apr - 04 Apr	Iberia	direct
24 Apr - 03 May	Iberia	direct
29 Apr - 03 May	Iberia	direct
29 Apr - 02 May	Iberia	direct
15 Apr - 02 May	Iberia	direct
30 Apr - 03 May	Smart Wings	direct

Also check the deals for one-way flights from Madrid to Prague in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Prague in April from 115€

Return flights