AirHint found the following cheapest return flights from Madrid (MAD) to Prague (PRG) in April 2026 (see full year).

Return flights

15 Apr - 19 Apr	Air Europa
13 Apr - 17 Apr	Iberia
10 Apr - 12 Apr	Iberia Express
10 Apr - 23 Apr	Iberia	direct
17 Apr - 30 Apr	Wizz Air Malta
17 Apr - 30 Apr	Iberia	direct
01 Apr - 04 Apr	KLM
30 Apr - 03 May	ITA Airways
23 Apr - 26 Apr	Iberia	direct
02 Apr - 05 Apr	KLM
02 Apr - 05 Apr	Smart Wings	direct
30 Apr - 03 May	Smart Wings	direct

Also check the deals for one-way flights from Madrid to Prague in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Prague in April from 172€

Return flights